Clinical Immunology and Allergy: Lupus an Autoimmune Condition


Journal of Clinical Immunology and Allergy is a world class open access journal intended to publish the cutting-edge research in the field of Immunology and Allergy.

Lupus is a long-term autoimmune disease in which the body's immune system becomes hyperactive and attacks normal, healthy tissue. Symptoms include inflammation, swelling, and damage to the joints, skin, kidneys, blood, heart, and lungs.

 Lupus is not a contagious disease. A person cannot transmit it sexually or in any other way to another person. However, in rare cases, women with lupus may give birth to children who develop a form of lupus. This is called neonatal lupus.

There are different kinds of lupus.

 Systemic lupus erythematosus: SLE is the most familiar type of lupus. It is a systemic condition. This means it has an impact throughout the body. The symptoms can range from mild to severe.

Discoid lupus erythematosus: In discoid lupus erythematosus (DLE) — or cutaneous lupus — symptoms affect only the skin. A rash appears on the face, neck, and scalp.The raised areas may become thick and scaly, and scarring may result. The rash may last from a number of days to several years, and it may recur.

Subacute cutaneous lupus erythematosus: Subacute cutaneous lupus erythematosus refers to skin lesions that appear on parts of the body that are exposed to the sun. The lesions do not cause scarring.

Drug-induced lupus: In around 10 percent of people with SLE, symptoms occur because of a reaction to certain prescription drugs. According to Genetics Home Reference, some 80 drugs may cause the condition.

Drugs that are commonly associated with this form of lupus are:

• Hydralazine, a hypertension medication
• Procainamide, a heart arrhythmia medication
• Isoniazid, an antibiotic used to treat tuberculosis (TB)

Causes: Lupus is an autoimmune condition, but the exact cause is unclear. Symptoms The symptoms of lupus occur in times of flare-ups. Between flare-ups, people usually experience times of remission, when there are few or no symptoms.

Lupus has a wide range of symptoms, including:

• fatigue
• a loss of appetite and weight loss
• pain or swelling in joints and muscles
• swelling in the legs or around the eyes
• swollen glands, or lymph nodes
• skin rashes, due to bleeding under the skin
• mouth ulcers • sensitivity to the sun
• fever
• headaches
• chest pain upon deep breathing
• unusual hair loss
• pale or purple fingers or toes from cold or stress (Raynaud's phenomenon)
• arthritis 

To provide with the more detailed information the journal accepts original manuscripts in the form of Research Articles, Review Articles, Clinical Reviews, Commentaries, Case Reports, Perspectives and Short Communications encompassing all aspects of Clinical Immunology and Allergy for publication in open access platform.

All the manuscript published by Clinical Immunology and Allergy are available freely online immediately after publication without any subscription charges or registration.

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Media Contact
Sana George
Journal Manager
Clinical Immunology and Allergy
WhatsApp: +1-947-333-4405