We are glad to introduce our Journal Reproductive Immunology that encompasses male and female reproductive which accepts manuscripts like Research articles, Review articles, Short commentary, Case reports ect.

Reproductive immunology refers to a field of medicine that studies interactions (or the absence of them) between the immune system and components related to the reproductive system, such as maternal immune tolerance towards the fetus, or immunological interactions across the blood-testis barrier. The concept has been used by fertility clinics to explain the fertility problems, recurrent miscarriages and pregnancy complications observed when this state of immunological tolerance is not successfully achieved. Immunological therapy is the new up and coming method for treating many cases of previously "unexplained infertility" or recurrent miscarriage

Experiments are undergoing to test the effectiveness of an immunocontraceptive vaccine that inhibits the fusing of spermatozoa to the zona pellucida. This vaccine is currently being tested in animals and hopefully will be an effective contraceptive for humans. Normally, spermatozoa fuse with the zona pellucida surrounding the mature oocyte; the resulting acrosome reaction breaks down the egg's tough coating so that the sperm can fertilize the ovum. The mechanism of the vaccine is injection with cloned ZP cDNA, therefore this vaccine is a DNA based vaccine. This results in the production of antibodies against the ZP, which stop the sperm from binding to the zona pellucida and ultimately from fertilizing the ovum.

Another vaccine in investigation is one against HCG. This immunization would produce antibodies against hCG and TT. Antibodies against hCG would prevent the maintenance of the uterus for a viable pregnancy therefore preventing conception. Another vaccine that is utilized is the peptide β-hCG that is more specific to hCG and a more rapid and effective response occurs in the absence of LH, FSH, and TSH.

Best regards,

Rose Marie
Managing Editor
Reproductive Immunology: Open Access

reprodimmunol[at]emedsci[dot]com