Immune System Modulation in the Treatment of Gynecological Malignancies.


The Journal Reproductive Immunology: Open Access aims to spread knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics related to the reproductive immunology. The open access journal is published by Insight Medical Publishing who hosts open access peer-reviewed journals as well as organizes conferences that hosts the work of researchers in a manner that exemplifies the highest standards in research integrity.

We are delighted to share one of our recent published scientific communications with you titled “Improving Outcomes through Immune System Modulation in the Treatment of Gynecological Malignancies”. The corresponding author Dr. Pranshu Mohindra has well demonstrated his research work and the following abstract says it:


The treatment of gynecological cancers continues to evolve with combination of different therapies. There has been a significant effort to induce stimulation of the immune system through treatment with interferons and interleukins in the past. More recently, the remarkable results of clinical trials demonstrating efficacy of checkpoint inhibitor immunotherapies in multiple cancer types has generated considerable interest within the gynecological community. Here, we review the findings of efforts to augment the humoral immune system and review the pre-clinical and clinical evidence for checkpoint inhibitors. The Abscopal effect, a phenomenon whereby localized radiation therapy results in immune mediated tumor regression in distant sites is currently also discussed in the context of gynecological cancers. The combination of various immunotherapies in gynecological cancer and emerging clinical evidence for the combinations may lead to improved treatment outcomes.

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Our Journal emphasizes high-level research and education. Original research articles, reviews, short communications, and letters to the editors in the field of Reproductive Immunology are welcome. Every effort is made to have a speedy and critical peer-review process. We always encourage new research works under the scope of our Journal.

Rose Marie
Reproductive Immunology: Open Access
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